I am unable to be completely impartial when it comes to genealogy software that you should use. I have only used Family Tree Maker, and that since I got online in 1994. I never had any complaint about FTM and it was always an easy program to use. For me, the big change came in 2008 when they changed the program for those using Vista. Or, at least that is my understanding of what happened. If you have better info, please comment.
All that said, I am using Family Tree Maker 2006 and still find it the easiest one for me to use. Yes, I am set in my ways, but I also subscribe to the “if it ain’t broke, don’t fix it” club. Perhaps, if you are happy using Vista (I use XP and prefer it, even choosing to buy my new computer with XP OS instead of Vista) and you begin using FTM’s current version, you might find it something to your liking because you haven’t used a prior version.
I did find a Genealogy Software Review 2008 that you might want to look over to help you make a decision. If you do decide to buy Family Tree Maker, I am an affiliate and you can use my link here.
One thing I would tell you is that it is important to register your FTM program when you first install it. You won’t get a lot of emails from Ancestry/Family Tree Maker, but it will alert you when there is an update. In order to save money, use your link in the Family Tree Maker program > Internet> Ancestry Website to upgrade. Ususally though, if you keep your email address updated with them, you will get an email from them too, letting you know you can save money as a prior purchaser when a new version comes out.